2026 ISM Update
Clinical Reasoning for Fluid and Dural System Impairments in the Integrated Systems Model
This is a hybrid combined online and in person course and it is expected that before the in person part of this course, the lectures will be watched and the articles provided will be read. You will be given non-refundable access to this online material as part of the registration deposit for the course.
Course objectives
Upon completion of this course, participants will be able to:
- Update the ISM concepts for finding drivers in the cranial, cervical, upper thorax and shoulder girdle regions and differentiating musculoskeletal drivers from dural and fluid system impairments.
- Review the anatomy of the deep cervical fascia and its importance for fluid supply and drainage of the cranium and spinal canal.
- Update assessment and release techniques for visceral fascial vectors from the thorax to the neck and cranium, neuromyofascial vectors to the cranium and selected suture restrictions within the cranium.
- Apply the osteopathic concept of the Primary Respiratory Mechanism (PRM) through the ISM framework as a meaningful task for assessing fluid dynamics within the cranium and spinal canal.
- Expand clinical reasoning beyond regional musculoskeletal assessment by recognizing when traditional musculoskeletal explanations are no longer sufficient and fluid system impairments should be considered within the Integrated Systems Model.
- Integrate foundational concepts of the lymphatic, glymphatic, venous and cerebrospinal fluid systems into existing ISM clinical reasoning to improve assessment prioritization, interpretation of findings and treatment planning.
- Interpret common clinical presentations—including pressure symptoms, positional symptoms, fluctuating symptoms, dizziness, cognitive fatigue and poor treatment carry-over—through the lens of pressure regulation, drainage and physiological adaptability.
- Interpret PRM findings, fluctuation patterns and related assessment findings to support clinical reasoning and clinical decision-making rather than relying solely on palpation findings.
- Apply practical assessment, treatment and patient education strategies that support pressure regulation, drainage and physiological adaptability within everyday physiotherapy practice.
Pre-Course Online Learning
Participants are required to complete the following online learning prior to attending the in-person course. These modules provide the foundational ISM concepts and anatomy that will be applied throughout the weekend.
Online Modules
The following modules are drawn from the new online ISM Series home study course that contains 30 hours of lectures, directed anatomy study, articles to read (they are provided) and directed reading in The Thorax book (D Lee 2018).
Module 1: Cranium, Cervical Spine, Upper Thorax & Shoulder Girdle Drivers – Part 2 ISM Series Lecture
Duration: 2 hours 10 minutes
Review of Functional Unit 2 assessment and driver identification for the cranium, cervical spine, upper thorax and shoulder girdle.
Module 2: Further Assessment of Part 2 Drivers – Cranium & Neck
Duration: 1 hour
This lecture provides a review of the deep cervical fascia and related anatomy essential for assessment and clinical reasoning within Functional Unit 2.
Pre-Course Reading
The purpose of these readings is simply to familiarize yourself with the terminology surrounding the lymphatic, glymphatic and cerebrospinal fluid systems before the course. You are not expected to master the physiology prior to attending. The in-person course will focus on integrating these concepts into Integrated Systems Model (ISM) clinical reasoning through assessment, treatment and clinical application.
Open-Access Review Articles
These articles will be provided for you in the online preparatory course material.
- Adamczyk LA et al. (2016). Lymph vessels: The forgotten second circulation in health and disease.
- Aalling N et al. (2015). The Glymphatic System: A Beginner’s Guide.
- Moore JE Jr., & Bertram CD. (2018). Lymphatic System Flows.
- Schwager S., & Detmar M. (2019). Inflammation and Lymphatic Function.
- Simon MJ., & Iliff JJ. (2016). Regulation of cerebrospinal fluid flow in neurodegenerative, neurovascular and neuroinflammatory disease.
In Person Program
Day 1 (Friday Afternoon)
1:00–1:30 pm Welcome & Course Overview
- Introduction
- Course objectives
- Overview of the weekend
1:30–3:00 pm Session 1
The Story – When Should We Expand Beyond Traditional MSK Clinical Reasoning?
This session introduces the first clinical question:
When is a musculoskeletal explanation no longer sufficient?
Using the patient’s story as the starting point, participants will develop advanced pattern recognition skills to identify when traditional biomechanical reasoning may not fully explain the presentation and when further assessment of the cranium, spinal dura and fluid system impairments should be considered within the Integrated Systems Model.
This session establishes when clinicians should broaden their clinical reasoning, how to select an appropriate screening task and how to prioritize assessment before moving hands-on.
Topics include
- Recognizing symptom patterns that warrant expanding clinical reasoning
- Identifying key subjective findings from the patient story
- Selecting an appropriate screening task
- Prioritizing assessment pathways
- Determining when an MSK driver explains the presentation
- Recognizing when no MSK correction adequately changes the task and a fluid system impairment should be considered
3:00–3:30 pm Coffee Break & Networking Time
3:30–7:00 pm Session 2
Is the Driver Musculoskeletal or a Fluid System Impairment?
Hands-on application of ISM assessment principles to determine whether the patient’s presentation is explained by a musculoskeletal driver or whether fluid system impairments should enter the clinical reasoning process.
Topics include
- Review of Functional Unit 2 Driver assessment using head and neck rotation (or neck flexion)
- Relationship between the cranium, cervical spine, upper thorax and pelvis via the spinal dura
- Recognizing when musculoskeletal corrections improve the task
- Recognizing when fluid system impairments should be considered
- Listening and vector interpretation
Day 2 (Saturday)
Treating the Mechanical Barriers to Optimal Fluid Dynamics
The focus of Day 2 is identifying and treating the musculoskeletal vectors that may influence pressure regulation, drainage and fluid dynamics before considering intracranial assessment.
8:30–10:00 am Session 3
If Fluid Is Impaired, Where Do We Start?
This session will cover the assessment and treatment of extracranial influences on pressure regulation and drainage.
Topics include
- Buccopharyngeal fascia
- Suprapleural membrane
- C7, TR1 and clavicular influences
- Treatment of extracranial vectors
10:00–10:30 am Coffee Break & Networking
10:30 am–12:30 pm Session 4
Drainage Before Cranium
Understanding treatment sequencing within the ISM framework.
Topics include
- Drainage pathways and their clinical significance
- The cerebellar tentorium within the context of the entire drainage system
- Treatment sequencing
- Clinical reasoning
12:30–1:30 pm Lunch & Networking
1:30–3:00 pm Session 5
Primary Respiratory Mechanism (PRM) Assessment and Interpretation
Topics include
- Assessment of the Primary Respiratory Mechanism
- Differentiating extracranial and intracranial vectors impeding the PRM
- Clinical significance of PRM findings
3:00–3:15 pm Coffee Break & Networking
3:15–4:30 pm Session 6
Intracranial Vectors and Clinical Integration
Topics include
- Articular vectors within the cranium – listening to detect and release techniques
- Suture mobilization
- Reassessment of PRM
- Reassessment of the original screening task
- Clinical integration and discussion
Day 3 (Sunday)
Understanding the Fluid Story Behind the Driver
Having identified the driver (Day 1) and addressed the musculoskeletal vectors influencing pressure regulation and drainage (Day 2), Day 3 explores how fluid system impairments influence clinical presentation, assessment findings and treatment planning within the Integrated Systems Model.
8:30–10:30 am Session 1
Understanding the Fluid Story – Why Does This Patient Present This Way?
This session explores how pressure regulation, drainage, fluid supply and physiological adaptability contribute to common clinical presentations.
Rather than studying fluid systems in isolation, lymphatic, glymphatic, venous and cerebrospinal fluid concepts are introduced as mechanisms that help explain patient presentation and guide clinical reasoning.
Topics include
- Pressure regulation, drainage and fluid supply
- Autonomic influences on physiological regulation
- Breathing, pressure management and adaptability
- Trauma, adaptation and allostatic load
- Why symptoms fluctuate over time
- Why treatment sometimes does not hold
- How fluid system impairments influence clinical reasoning
Broader clinical considerations
- Venous thoracic outlet presentations
- Craniocervical instability
- Upper cervical influences
- First rib syndromes
- Tongue–hyoid relationships and pressure regulation
10:30–11:00 am Coffee Break & Networking
11:00 am–12:30 pm Session 2
Interpreting Fluid Findings – What Are These Findings Telling Us?
Discussion and practical application of fluid assessment findings within clinical reasoning.
Discussion topics
- What do PRM findings mean?
- What do fluctuation signs mean?
- What do asynchronous patterns mean?
- What might these findings tell us about pressure regulation?
- What might they tell us about drainage capacity?
- What might they tell us about system adaptability?
- How might they influence assessment priorities and treatment planning?
Practical Session
- PRM assessment
- Fluctuation assessment
- Clinical interpretation
- Case discussion
- Clinical decision-making
12:30–1:30 pm Lunch & Networking
1:30–4:30 pm Session 3
Practical Applications for Optimizing Flow – Fluid Through a Physiotherapy Lens
Translating fluid concepts into practical assessment, treatment and patient education strategies that clinicians can immediately integrate into everyday physiotherapy practice.
Lab 1 – Creating Capacity Before Flow
Assessment and treatment of regions influencing pressure regulation and drainage.
- Upper thorax
- Thoracic outlet
- Head and neck
- Cervical drainage pathways
- Optimizing regional capacity before addressing intracranial findings
Lab 2 – Restoring the Pumps
Foundational treatment strategies supporting fluid movement.
- BIG 6
- Pectoral lift
- Lung pump
- Pedal pump
- Diaphragm techniques
- Development of individualized home programs
Lab 3 – Integrating Fluid Thinking into Everyday Physiotherapy Practice
Applying fluid concepts within existing physiotherapy practice.
- Breathing strategies
- Movement and exercise
- Lifestyle considerations
- Recovery and pacing
- Patient education
- Integrating fluid concepts into existing ISM clinical reasoning
Come join Diane Lee & Judit Orban and catch up on their collaborative learning journey over the last 6 years that has led to a deeper appreciation of ISM for the cranium, upper thorax and pelvis in relationship to the fluid systems of the body.
This course is limited to those who have done the ISM Series since 2014 since much as changed in the last decade that will not be updated in this course. For those of you who haven’t done the ISM Series in the last 6 years, Diane highly encourages you to check out the new online ISM Series home study course to update yourself prior to attending this course. The more you review the more you will get out of this update course.

Dear Diane, I wanted to thank you for putting your heart and soul into teaching the course this last weekend. It really helped integrate all the loose ends (e.g. sternoclavicular joint, cranium, pelvis/ pelvic floor, elbow, wrist,) and pull the pieces together for me.
I went forth confident that I could figure things out given the framework (form) and being empowered to be creative (freedom). The journey ahead excites me with all the possibilities for improving quality of movement and life for my patients.
Thank you for the empowerment and for passing on this knowledge.
Trina